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1.

518
Accesses

Research   Open Access Highly Accessed

A simulation study comparing supertree and combined analysis methods using SMIDGen

M Shel Swenson, François Barbançon, Tandy Warnow, C Randal Linder Algorithms for Molecular Biology 2010, 5:8 (4 January 2010)

Abstract | Full text | PDF | PubMed

2.

430
Accesses

Research   Open Access Highly Accessed

Efficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training

Tin Y Lam, Irmtraud M Meyer Algorithms for Molecular Biology 2010, 5:38 (9 December 2010)

Abstract | Full text | PDF | PubMed

3.

403
Accesses

Research   Open Access Highly Accessed

Coexpression and coregulation analysis of time-series gene expression data in estrogen-induced breast cancer cell

Anirban Bhar, Martin Haubrock, Anirban Mukhopadhyay, Ujjwal Maulik, Sanghamitra Bandyopadhyay, Edgar Wingender Algorithms for Molecular Biology 2013, 8:9 (23 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

302
Accesses

Software article   Open Access Highly Accessed

ViennaRNA Package 2.0

Ronny Lorenz, Stephan H Bernhart, Christian Höner zu Siederdissen, Hakim Tafer, Christoph Flamm, Peter F Stadler, Ivo L Hofacker Algorithms for Molecular Biology 2011, 6:26 (24 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

255
Accesses

Research   Open Access Highly Accessed

Estimation of alternative splicing isoform frequencies from RNA-Seq data

Marius Nicolae, Serghei Mangul, Ion I Măndoiu, Alex Zelikovsky Algorithms for Molecular Biology 2011, 6:9 (19 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

245
Accesses

Research   Open Access Highly Accessed

Differential co-expression framework to quantify goodness of biclusters and compare biclustering algorithms

Burton Chia, R Krishna Murthy Karuturi Algorithms for Molecular Biology 2010, 5:23 (28 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

239
Accesses

Research   Open Access Highly Accessed

Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules

Valentina Boeva, Julien Clément, Mireille Régnier, Mikhail A Roytberg, Vsevolod J Makeev Algorithms for Molecular Biology 2007, 2:13 (10 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

237
Accesses

Research   Open Access Highly Accessed

A normalization strategy for comparing tag count data

Koji Kadota, Tomoaki Nishiyama, Kentaro Shimizu Algorithms for Molecular Biology 2012, 7:5 (5 April 2012)

Abstract | Full text | PDF | PubMed

9.

198
Accesses

Research   Open Access Highly Accessed

Gene Ontology consistent protein function prediction: the FALCON algorithm applied to six eukaryotic genomes

Yiannis AI Kourmpetis, Aalt DJ van Dijk, Cajo JF ter Braak Algorithms for Molecular Biology 2013, 8:10 (27 March 2013)

Abstract | Provisional PDF | PubMed

10.

188
Accesses

Research   Open Access

Fast calculation of the quartet distance between trees of arbitrary degrees

Chris Christiansen, Thomas Mailund, Christian NS Pedersen, Martin Randers, Martin Stissing Algorithms for Molecular Biology 2006, 1:16 (25 September 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

185
Accesses

Research   Open Access

An enhancement of binary particle swarm optimization for gene selection in classifying cancer classes

Mohd Saberi Mohamad, Sigeru Omatu, Safaai Deris, Michifumi Yoshioka, Afnizanfaizal Abdullah, Zuwairie Ibrahim Algorithms for Molecular Biology 2013, 8:15 (24 April 2013)

Abstract | Provisional PDF | PubMed

12.

180
Accesses

Research   Open Access Highly Accessed

Wrapper-based selection of genetic features in genome-wide association studies through fast matrix operations

Tapio Pahikkala, Sebastian Okser, Antti Airola, Tapio Salakoski, Tero Aittokallio Algorithms for Molecular Biology 2012, 7:11 (2 May 2012)

Abstract | Full text | PDF | ePUB | PubMed

13.

176
Accesses

Research   Open Access Highly Accessed

Invariants and Other Structural Properties of Biochemical Models as a Constraint Satisfaction Problem

Sylvain Soliman Algorithms for Molecular Biology 2012, 7:15 (29 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

174
Accesses

Research   Open Access

Characteristics of predictor sets found using differential prioritization

Chia Ooi, Madhu Chetty, Shyh Teng Algorithms for Molecular Biology 2007, 2:7 (4 June 2007)

Abstract | Full text | PDF | PubMed

15.

168
Accesses

Research   Open Access

Ultrametric networks: a new tool for phylogenetic analysis

Alberto Apostolico, Matteo Comin, Andres Dress, Laxmi Parida Algorithms for Molecular Biology 2013, 8:7 (5 March 2013)

Abstract | Provisional PDF | PubMed

16.

164
Accesses

Research   Open Access Highly Accessed

A tree-based method for the rapid screening of chemical fingerprints

Thomas G Kristensen, Jesper Nielsen, Christian NS Pedersen Algorithms for Molecular Biology 2010, 5:9 (4 January 2010)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Using a kD grid and Multibit tree to screen molecular fingerprint databases for chemical compounds with high similarity scores, based on the Tanimoto coefficient, is three times quicker than earlier methods, allowing researchers to identify novel drug candidates more efficiently.

17.

162
Accesses

Research   Open Access Highly Accessed

DIALIGN-TX: greedy and progressive approaches for segment-based multiple sequence alignment

Amarendran R Subramanian, Michael Kaufmann, Burkhard Morgenstern Algorithms for Molecular Biology 2008, 3:6 (27 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

160
Accesses

Research   Open Access Highly Accessed

Maximum Parsimony on Phylogenetic networks

Lavanya Kannan, Ward C Wheeler Algorithms for Molecular Biology 2012, 7:9 (2 May 2012)

Abstract | Full text | PDF | PubMed

19.

153
Accesses

Research   Open Access Highly Accessed

Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments

Vadim Farztdinov, Fionnuala McDyer Algorithms for Molecular Biology 2012, 7:29 (2 November 2012)

Abstract | Full text | PDF | PubMed

20.

152
Accesses

Research   Open Access Highly Accessed

Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps

Peter Meinicke, Thomas Lingner, Alexander Kaever, Kirstin Feussner, Cornelia Göbel, Ivo Feussner, Petr Karlovsky, Burkhard Morgenstern Algorithms for Molecular Biology 2008, 3:9 (26 June 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

149
Accesses

Research   Open Access Highly Accessed

Multiple sequence alignment with user-defined anchor points

Burkhard Morgenstern, Sonja J Prohaska, Dirk Pöhler, Peter F Stadler Algorithms for Molecular Biology 2006, 1:6 (19 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

149
Accesses

Software article   Open Access Highly Accessed

Jane: a new tool for the cophylogeny reconstruction problem

Chris Conow, Daniel Fielder, Yaniv Ovadia, Ran Libeskind-Hadas Algorithms for Molecular Biology 2010, 5:16 (3 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

149
Accesses

Research   Open Access

LocARNAscan: Incorporating thermodynamic stability in sequence and structure-based RNA homology search

Sebastian Will, Michael F. Siebauer, Steffen Heyne, Jan Engelhardt, Peter F. Stadler, Kristin Reiche, Rolf Backofen Algorithms for Molecular Biology 2013, 8:14 (20 April 2013)

Abstract | Provisional PDF | PubMed

24.

146
Accesses

Research   Open Access

Reconciliation and local gene tree rearrangement can be of mutual profit

Thi Hau Nguyen, Vincent Ranwez, Stéphanie Pointet, Anne-Muriel Arigon Chifolleau, Jean-Philippe Doyon, Vincent Berry Algorithms for Molecular Biology 2013, 8:12 (8 April 2013)

Abstract | Provisional PDF | PubMed

25.

144
Accesses

Meeting report   Open Access Highly Accessed

Data Mining in Bioinformatics (BIOKDD)

Mohammed J Zaki, George Karypis, Jiong Yang Algorithms for Molecular Biology 2007, 2:4 (11 April 2007)

Abstract | Full text | PDF | PubMed

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