Table 2

Prediction performance of ExAlt. Sensitivity (Sens) and Specificity (Spec) are shown for exons.


Constitutive
Cassete
Multiple Splice
Intron Retention
All Exons

Sens
Spec
Sens
Spec
Sens
Spec
Sens
Spec
Sens
Spec

ExAlt-Exon
100
96
100
89
67
94
61
89
84
94
N-SCAN-Exon Union
100
86
100
89
65
79
55
78
82
84
Augustus-Exon Union
100
82
100
81
63
77
52
73
81
79
SNAP-Exon Union
100
77
100
79
64
74
51
76
81
77
SNAP+N-SCAN-Exon Union
100
73
100
74
69
68
57
70
83
72
Augustus+N-SCAN-Exon Union
100
79
100
77
68
73
57
68
83
76
Aug.+SNAP+N-SCAN-Exon Union
100
70
100
69
71
64
60
64
84
67

Columns are organized by exon type: Constitutive, Cassette, Multiple Splice, Intron Retention, and all exons counted together (All Exons). Row 1 shows ExAlt performance using an input exon and default parameter settings (ExAlt-Exon). Rows 2–6 show the union of different combinations of three gene finders (N-SCAN, SNAP, and Augustus) plus the input exon. (Aug. = Augustus)

Allen and Salzberg Algorithms for Molecular Biology 2006 1:14   doi:10.1186/1748-7188-1-14